The Center’s digital archive project, The American Influenza Epidemic of 1918–1919: A Digital Encyclopedia, which made its public debut at www.influenzaarchive.org on October 10, 2012, is a collaborative venture involving the Center, MPublishing, and the Division of Global Migration and Quarantine at the Centers for Disease Control and Prevention. Additional funding from the National Endowment for the Humanities included the prestigious We the People designation acknowledging our efforts to enrich the teaching, study, and understanding of American history and culture.

The website is an open access digital collection of archival, primary, and interpretive materials related to the history of the 1918–1919 influenza pandemic in the United States. Features like keyword metatagging help guide the reader and serve as templates for self-guided research projects.